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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T77647 | Tubulin polymerization-IN-43 | Apoptosis , Microtubule Associated | |
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell c... | |||
T77651 | Tubulin polymerization-IN-47 | Microtubule Associated | |
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 an... | |||
T77728 | Tubulin polymerization-IN-55 | Microtubule Associated | |
Tubulin polymerization-IN-55 is a potent Tubulin Polymerization inhibitor with potential anti-angiogenic and anti-tumour activity, showing anti-proliferative effects against A549, K562, HepG2, MDA-MB-231 and HFL-1. | |||
T9504 | MAP4343 | Microtubule Associated | |
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n... | |||
T9595 | LP-261 | Microtubule Associated | |
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. | |||
T10460 | Batabulin | T138067 | Apoptosis , Microtubule Associated |
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to ce... | |||
T61069 | Tubulin polymerization-IN-15 | ||
Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1]. | |||
T60902 | Tubulin polymerization-IN-31 | ||
Tubulin polymerization-IN-31 (Compound 4c) has antitumor activity and induces apoptosis of cancer cell. Tubulin polymerization-IN-31 is an inhibitor of tubulin polymerization with an IC 50 value of 3.64 μM [1]. | |||
T60735 | Tubulin polymerization-IN-22 | ||
Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22 is an inhibitor of tubulin polymerization (IC 50 = 8.1 μM) [1]. | |||
T60758 | Tubulin polymerization-IN-36 | ||
Tubulin polymerization-IN-36 is able to be used in cancer research, for example, lymphomas. Tubulin polymerization-IN-36 binds to the colchicine site of tubulin and inhibits colchicine binding, that is an inhibitor of tu... | |||
T79268 | Tubulin polymerization-IN-42 | ||
Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1]. | |||
T61129 | Tubulin polymerization-IN-27 | ||
Tubulin polymerization-IN-27 (compound 5j) is an inhibitor of tubulin polymerization. It has the ability to halt the cell cycle specifically at the G2/M phase and also induce apoptosis [1]. | |||
T61532 | Tubulin polymerization-IN-6 | ||
Tubulin polymerization-IN-6 (compound 5f) is a potent inhibitor of tubulin polymerization, with an IC50 of 1.09 μM. It not only inhibits cell migration and tube formation but also has anti-angiogenic properties. Addition... | |||
T61482 | Tubulin polymerization-IN-13 | ||
Tubulin polymerization-IN-13 (Compound 4f) is a potent inhibitor of tubulin polymerization, with an IC50 value of 0.37 μM. It displays significant anti-proliferative effects against cancer cells, inducing apoptosis and e... | |||
T62121 | Tubulin polymerization-IN-3 | ||
Tubulin polymerization-IN-3 is a potent inhibitor of microtubulin polymerization (IC50: 3.84 μM) and induces apoptosis in colon cancer cells. | |||
T63580 | Tubulin polymerization-IN-21 | ||
Tubulin polymerization-IN-21 is an inhibitor of microtubulin polymerization that disrupts cell integrity and affects glucose metabolism, and has anticancer effects. | |||
T63111 | Tubulin polymerization-IN-33 | ||
Tubulin polymerization-IN-33 is an [1,2] inhibitor of oxazoloisoindole microtubulin polymerization and is a good anti-proliferative agent for NCI series cancer cells. | |||
T79887 | Tubulin polymerization-IN-49 | ||
Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell cycle arrest at the G2/M phase and triggering apoptosis. This... | |||
T79645 | Tubulin polymerization-IN-48 | ||
Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network. It impedes the proliferation of neuroblastoma cancer cells, exhibiting IC50 values of 7... | |||
T62206 | Tubulin polymerization-IN-19 | ||
Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer. |